SPEAKER PROFILE |
 Prof. Uwe Pieles FHNW (University of applied sciences North West Switzerland), School of life Sciences in Muttenz SWITZERLAND |
BIOPRINT- 3D Printing, new routes towards biofunctional materials
Abstract
3D printing or rapid manufacturing techniques emerged during the last decades as key technology in modern engineering. Recently these methods also find their way into the field of medicine, in particular in design and manufacturing of e.g. tailored patient specific implants, prostethic devices, tools for surgery and most recently also for cells for tissue engineering.
With the project “BIOPRINT” we aim for the development of ceramic bone substituent structures for load bearing applications. Mayor drawback of current implants is that they are either produced from stainless steel or titanium alloys which have to remain as foreign material in the body but giving the required mechanical strength e.g. hip implants or produced from bioceramics like hydroxyapatite or ß-TCP which are finally fully resorbed by the human body but are brittle and lack the necessary strength for covering larger bone defects. In our study we will present data utilizing 3D printing technologies, bioceramic materials and particular binders to significantly improve the mechanical properties of the resulting scaffold structures. We further present recent data using bone cells to further improve the implant properties and to alter the surface morphology of the resulting scaffolds.
In the second part of the presentation we willl present our latest results using biodegradable composite materials for applications in laser tissue soldering. Here the scaffolds are produced by either solvent casting in combination with electrospinning of bioaugmented polymers or most recently by 3D printing techniques to produce biofunctional scaffollds. The soldering process is induced by tailored nanoparticles.
Main research activities of the group: Surface science, surface chemistry, supra molecular chemistry, material sciences with strong focus on biomaterials and implants. Nanomaterials for biomedical applications.
Awards: International Collano Recognition Award 2007 Figgemeier, Chabrecek, Pieles «Development of flexible textile based dye sensitized solar Cells»
Publications/Patents: more than 50 peer reviewed Publications and patents
With the project “BIOPRINT” we aim for the development of ceramic bone substituent structures for load bearing applications. Mayor drawback of current implants is that they are either produced from stainless steel or titanium alloys which have to remain as foreign material in the body but giving the required mechanical strength e.g. hip implants or produced from bioceramics like hydroxyapatite or ß-TCP which are finally fully resorbed by the human body but are brittle and lack the necessary strength for covering larger bone defects. In our study we will present data utilizing 3D printing technologies, bioceramic materials and particular binders to significantly improve the mechanical properties of the resulting scaffold structures. We further present recent data using bone cells to further improve the implant properties and to alter the surface morphology of the resulting scaffolds.
In the second part of the presentation we willl present our latest results using biodegradable composite materials for applications in laser tissue soldering. Here the scaffolds are produced by either solvent casting in combination with electrospinning of bioaugmented polymers or most recently by 3D printing techniques to produce biofunctional scaffollds. The soldering process is induced by tailored nanoparticles.
Bio
Born in Germany 21.07.59 in Warburg/Germany. Grown up in Bielefeld /Germany. Studies in Chemistry at the Universities Bielefeld and Göttingen (1981-1985). Diplomathesis (1985) and PHD-Thesis (1988) at the MaxPlanck Institute for experimental medicine in the field of chemically modified oligonucleotides under the supervision of Prof.Dr. F.Cramer. !989-1991 Postdoc (EMBL-Fellow) at the EMBL (European molecular biology laboratory). 1991-1996 Labhead Central research laboratories Ciba/Novartis Switzerland (Basel). 1997-2000 Groupleader pharmaceutical research Altana AG Germany (Konstanz). Since 2000 Head of nanotechnology/materials sciences and Professor at the FHNW (University of applied sciences North West Switzerland) School of life Sciences in Muttenz (Switzerland). Uwe Pieles is author and Coauthor of more than 50 publications, patents and patent applications.Main research activities of the group: Surface science, surface chemistry, supra molecular chemistry, material sciences with strong focus on biomaterials and implants. Nanomaterials for biomedical applications.
Awards: International Collano Recognition Award 2007 Figgemeier, Chabrecek, Pieles «Development of flexible textile based dye sensitized solar Cells»
Publications/Patents: more than 50 peer reviewed Publications and patents